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Malaria-Free

Project Noah believes that we can save lives by delivering the latest in science and technology to those with the greatest needs. We work with partners to develop and provide effective vaccines, drugs, diagnostics and to develop innovative approaches to deliver health services to those who need it most. We invest heavily in developing new vaccines to prevent infectious diseases that impose the greatest burden.

In 2017, one of the key Global Healthcare initiatives is focusing on the elimination of Malaria. Malaria is preventable and treatable, and history shows that it can be curbed and eliminated.

We have the opportunity to accelerate progress toward elimination in all countries by improving the delivery of existing interventions as well as developing new tools and formulating new strategies that target not just malaria-transmitting mosquitoes but also the parasite itself, which can survive in humans for more than 10 years. By mobilizing the required commitment and resources, we can achieve global eradication and save many millions of lives.

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Our Strategy

Our Malaria strategy is based on a core set of foundational principles that support our evolving strategic choices.
  • Malaria eradication is defined as removing the parasites that causes malaria from the human population. Simply interrupting transmission is not sufficient to achieve eradication.
  • Eradication can be accelerated by new drug regimens and strategies that lead to complete parasitological cure of the individual. Current artemisinin-based regimens achieve only clinical cure of the individual and do not eliminate the forms of the parasites that are responsible for continued transmission.
  • The majority of malaria infections occur in asymptomatic people, whom are conduits of continued transmission. A successful and accelerated eradication effort will target asymptomatic infections through community-based efforts.
  • Emerging resistance to current drugs and insecticides is an immediate threat to recent gains and an obstacle to future progress. Use of current tools and development of new tools should be guided by this evolutionary imperative.
  • Malaria is biologically and ecologically different throughout the world. Malaria eradication will depend on strategies developed and implemented on a local or regional level.

  • We concentrate our resources on areas where we can identify significant leverage points, and we assume risks that are more challenging for others to undertake. Potentially transformative measures that could accelerate malaria eradication include single-dose treatments that are safe and well tolerated, highly sensitive diagnostic tests, and vaccines that prevent infection or block transmission.
    Emerging resistance to insecticides and drugs is the most important biological threat to the goal of eradication, therefore we are investing in the development of new tools and strategies to prevent or delay resistance. We also advocate for sustained and increased funding of malaria-related efforts by the governments in donor countries as well as countries where malaria is endemic.